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Dr. Daniel Nelson - Representative Publications Print Print   Email Email  

Manuscripts
Koller, T., Nelson, D., Nakata, M., Kreutzer, M., Fischetti, V.A., Glocker, M.O., Podbielski, A., & Kreikemeyer, B. (2007) PlyC, A Novel Enzyme for Compartment Dependent Proteomics of Group A Streptococci. Proteomics 7: In press.

Porter, C.J., Schuch, R., Pelzek, A.J., Buckle, A.M., McGowan, S., Wilce, M.C.J., Rossjohn, J., Russell, R., Nelson, D., Fischetti, V.A., & Whisstock, J.C. (2007) The 1.6 Crystal Structure of the Catalytic Domain of PlyB, a Bacteriophage Lysin Active Against Bacillus anthracis. J. Mol. Biol. 366: 540-550.

Fischetti, V.A., Nelson, D., & Schuch, R. (2006) Reinventing Phage Therapy: Are the Parts Greater than the Sum? Nature Biotechnol. 24: 1508-1511.

Nelson, D., Schuch, R., Chahales, P. Zhu, S., & Fischetti, V.A. (2006) PlyC: A Multimeric Bacteriophage Lysin. Proc. Natl. Acad. Sci. U.S.A. 103: 10765-10770.

Yoong, P., Schuch, R., Nelson, D., & Fischetti, Vincent A. (2006) PlyPH, A Bacteriolytic Enzyme with a Broad pH Range of Activity and Lytic Action against Bacillus anthracis. J. Bacteriol. 188: 2711-2714.

Sabharwal, H., Michon, F., Nelson, D., Dong, W., Fuchs, K., Manjarrez, R.C., Sarkar, A., Viteri-Jackson, A., Rodriguez, R.S., Blake, M., & Zabriskie, J.B. (2006) Group A Streptococcus (GAS) Carbohydrate as an Immunogen for Protection against GAS Infection. J. Infect. Dis. 193: 129-135.

Cheng, Q., Nelson, D., Zhu, S., & Fischetti, V.A. (2005) Removing Group B Streptococci Colonizing the Vagina and Pharynx of Mice with a Bacteriophage Lytic Enzyme. Antimicrob. Agents Chemother. 49: 111-117.

Nelson, D. (2004) Phage Taxonomy: We Agree to Disagree. J. Bacteriol. 186: 7029-7031.

Yoong, P., Schuch, R., Nelson, D., & Fischetti, V.A. (2004) Identification of a Broadly Active Phage Lytic Enzyme with Lethal Activity against Antibiotic Resistant Enterococcus faecalis and Enterococcus faecium. J. Bacteriol. 186: 4808-4812.

Nelson, D., Schuch, R., Zhu, S., Tscherne, D., & Fischetti, V.A. (2003) The Genomic Sequence of C1: The First Streptococcal Phage. J. Bacteriol. 185: 3325-3332.

Schuch, R., Nelson, D., & Fischetti, V.A. (2002) Identification of a Bacteriolytic Agent that can Rapidly and Specifically Detect and Kill Bacillus anthracis. Nature 418: 884-889. (Cover photo)

Goldstein, J.M., Nelson, D., Kordula, T., Mayo, J.A., & Travis, J. (2002) Extracellular Arginine Aminopeptidase from Streptococcus gordonii FSS2. Infect. Immun. 70: 836-843.

Loeffler, J.M., Nelson, D., & Fischetti, V.A. (2001) Rapid Killing of Streptococus pneumoniae with a Bacteriophage Cell Wall Hydrolase: A New Approach to Eliminate Mucosal Carriage. Science 294: 2170-2172.

Nelson, D., Loomis, L., & Fischetti, V.A. (2001) Prevention and Elimination of Upper Respiratory Colonization of Mice by Group A Streptococci Using a Bacteriophage Lytic Enzyme. Proc. Natl. Acad. Sci. U.S.A. 98: 4107-4112.

Nelson, D., Goldstein, J.M., Boatright, K., Harty, D.W.S., Cook, S.L., Hickman, P.J., Potempa, J., Travis, J., & Mayo, J.A. (2001) pH-regulated Secretion of a Glyceraldehyde-3-Phosphate Dehydrogenase from Streptococcus gordonii FSS2: Purification, Characterization and Cloning of the Gene Encoding this Enzyme. J. Dent. Res. 80: 371-377.

Banbula, A., Bugno, M., Goldstein, J., Yen, J., Nelson, D., Travis, J., & Potempa, J. (2000) Emerging Family of Proline-Specific Peptidases of Porphyromonas gingivalis: Purification and Characterization of Serine Dipeptidyl Peptidase, a Structural and Functional Homologue of Mammalian Prolyl Dipeptidyl Peptidase IV. Infect. Immun. 68: 1176-1182.

Rapala-Kozik, M., Potempa, J., Nelson, D., Kozik, A., & Travis, J. (1999) Comparative Cleavage Sites Within the Reactive-Site Loop of Native and Oxidized a1-Proteinase Inhibitor by Selected Bacterial Proteinases. Biol. Chem. 380: 1211-1216.

Nelson, D., Potempa, J., Kordula, T., & Travis, J. (1999) Purification and Characterization of a Novel Cysteine Proteinase (Periodontain) from Porphyromonas gingivalis: Evidence for a Role in the Inactivation of Human a1-Proteinase Inhibitor. J. Biol. Chem. 274: 12245-12251.

Banbula, A., Mak, P., Bugno, M., Silberring, J., Dubin, A., Nelson, D., Travis, J., & Potempa, J. (1999) Prolyl Tripeptidyl Peptidase from Porphyromonas gingivalis: A Novel Enzyme with Possible Pathological Implications for the Development of Periodontitis. J. Biol. Chem. 274: 9246-9252.

Nelson, D., Potempa, J., & Travis, J. (1998) Inactivation of a1-Proteinase Inhibitor as a Broad Screen for Detecting Proteolytic Activities in Unknown Samples. Anal. Biochem. 260: 230-236.

Potempa, J., Mikolajczyk-Pawlinska, J., Brassell, D., Nelson, D., Thogersen, I.B., Enghild, J.J., & Travis, J. (1998) Comparative Properties of Two Cysteine Proteinases (Gingipains R), the Products of Two Related but Individual Genes of Porphyromonas gingivalis. J. Biol. Chem. 273: 21648-21657.

Roh, D.D., Kwak, P., Nelson, D., Kamanna, V.S., & Kirschenbaum, M.A. (1993) Effect of Dietary Cholesterol on Rat Glomerular Cholesterol Esterase. Am. J. Nephrol. 13: 478-482.

Book Chapters
Schuch, R., Fischetti, V.A., & Nelson, D. (2007) A Genetic Screen to Identify Bacteriophage Lysins. In M. Clokie & A. Kropinski (eds.): Bacteriophages: Methods and Protocols. Humana.

Potempa, J., Kantyka, T., & Nelson, D. (2007) Serpin Interaction with Bacterial Peptidases. In G. A. Silverman & D. A. Lomas (eds.), Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity. World Scientific Publishing Co.

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