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Dr. Mervyn Monteiro Publications Print Print   Email Email  

S. Janicki and Monteiro, M.J. 1997. Increased Apoptosis arising from Increased Expression of the Alzheimer’s Disease-associated Presenilin-2 Mutation (N141I). J. Cell Biol. 139:485-495.

Mical, T. and Monteiro, M.J. 1998. The role of sequences unique to nuclear intermediate filaments in the targeting and assembly of human lamin B: Evidence for lack of interaction of lamin B with its putative receptor. J. Cell Science 111:3471-3485.

Judge, S.I.V., Monteiro, M.J., Yeh, J.Z. and Bever, C.T. 1999. Inactivation gating and 4-AP sensitivity in human brain Kv1.4 potassium channel. Brain Research 831:43-54.

Stabler, S.M. Ostrowski, L.L. Janicki, S.M. and Monteiro, M.J. 1999. A myristoylated calcium binding protein that preferentially interacts with the Alzheimer’s Disease Presenilin 2 protein. J. Cell Biol. 145:1277-1292.

Janicki S.M. and Monteiro, M.J. 1999. Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer’s Disease PS2(N141I) mutant. Am. J. Pathol. 155:135-144.

Mah, A., Perry, G., Smith M.A., and Monteiro, M.J. 2000. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J. Cell Biol. 151: 847-862.

Janicki, S.M., Stabler, S.M. and Monteiro, M.J. 2000. Familial Alzheimer’s Disease Presenilin-mutants potentiate cell cycle arrest. Neurobiol. of Aging 21:829-836.

Massey, L.K., Mah, A.L., Ford, D.L., Miller, J., Liang, J., Doong, H., and Monteiro, M.J. 2004. Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins. J. Alzheimer’s Disease 6:79-92.

Mical, T. Luther, P. and Monteiro, M.J. 2004. Intracellular assembly and sorting of intermediate filament proteins: role of the 42 amino acid lamin insert. Exp. Cell Res. 295:183-193.

P. Feng, Scott, C.W., Cho, N-H., Nakamura, H., Chung, Y-H., Monteiro, M.J. and Jung, J.U. 2004. Kaposi’s Sarcoma-Associated Herpes virus K7 Protein Targets a UBL/UBA Containing Protein to Promote Protein Degradation. Mol. Cell Biol. 24:3938-3948.

Gu, L., Troncoso, J.C, Wade, J.B. and Monteiro, M.J. 2004. In vitro assembly properties of mutant and chimeric intermediate filament proteins: insight into the function of sequences in the rod and end domains of the proteins. Exp. Cell Res. 298: 249-261.

Zhu,J., S. Stabler, J. Ames, I. Baskakov and Monteiro, M.J. 2004 Calcium-binding sequences in calmyrin regulate interaction with presenilin-2. Exp. Cell Res. 300: 440-454.

Massey, L.K., Mah, A.L., and Monteiro, M.J. 2005. Ubiquilin Regulates Presenilin Endoproteolysis and Modulates g-secretase Components, Pen-2 and Nicastrin. Biochem. J. 391:513-525.

Wang H, Lim PJ, Yin C, Rieckher M, Vogel BE, and Monteiro M.J. 2006. Suppression of Polyglutamine-Induced Toxicity in Cell and Animal Models of Huntington's Disease by Ubiquilin. Hum. Mol. Genet. 15:1025-1041.

White C, Yang J, Monteiro MJ, and Foskett JK. 2006. CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel. J. Biol. Chem. 281:20825-20833.

Ford DL, and Monteiro MJ. 2006. Dimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilins. Biochem .J. 399:397-404.

Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, and Monteiro MJ. 2006. Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation. J. Cell Sci. 119:4011-4024.

Yang H, Zhong X, Ballar P, Luo S, Shen Y, Rubinsztein DC, Monteiro MJ, and Fang S. 2007. Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin. Exp .Cell Res. 313:538-50.

Wang H, and Monteiro MJ. 2007. Ubiquilin overexpression reduces GFP-polyalanine-induced protein aggregates and toxicity. Exp Cell Res 313:2810-2820.

Wang H, and Monteiro MJ. 2007. Ubiquilin overexpression enhances the degradation of expanded polyglutamine proteins. Biochem. Biophys. Res. Commun.360:423-427.

Ford D, and Monteiro MJ. 2007. Studies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2. Biochemistry 46:8827-8837.

Wang H, Lim P, Karbowski M, and Monteiro MJ. 2009. Effects of overexpression of Huntingtin proteins on mitochondria integrity. Hum. Mol. Gen. 18: 737-752.

Lim P, Danner R, Liang J, Doong H, Yin C, Harman C, Srinivasan D, Rothernberg C, Wang H, Ye Y, Fang S, and Monteiro MJ. 2009. Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD, J Cell Bio (in press).

 

 

 

 

 

 

 

 

 

 

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