WU LAB Drosophila Immunity

Selected Publications

Ivory, A., K. Randle, L. Wu.  Cellular Immune Responses in Drosophila melanogaster, in Nucleic Acids and Molecular Biology, volume edited by H. Heine, Springer, 2007.

Wu, L., N. Silverman.  Fighting Infection Fly-Style.  Fly, 1(2): 106-109 (2007).

Pal, S., J. Wu, L. Wu.  Microarray analyses reveal distinct roles for Rel proteins in the Drosophila immune response.  Dev. Comp. Immunology, in press (2007).

Wu, J., K. Randle, L. Wu.  Innate immune responses are linked to the detection of nutritional state in Drosophila melanogaster.  Cellular Microbiology, 9(4): 1073-1085 (2007).

Pal, S., R. St.Leger, L. Wu.  Fungal peptide Destruxin A plays a specific role in suppressing the innate immune response in Drosophila melanogaster.  JBC 282(12): 8969-8977 (2007).

Pal, S., L.Wu. Lessons from the fly: Pattern Recognition in Drosophila melanogaster , in Target Pattern Recognition in Innate Immunity , edited by U. Kishore, Springer/Landes Bioscience, 2006. [pdf]

Zambon, R., V. Vakharia, L. Wu. RNAi is an antiviral immune response against a dsRNA virus in Drosophila melanogaster. Cellular Microbiology 8(5): 880-889 (2006). [pdf]

Garver, L., J. Wu, L. Wu. The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila melanogaster. PNAS 103: 660-665 (2006). Note: The first two authors contributed equally. [pdf]

Zambon, R., M. Nandakumar, V. Vakharia, L. Wu. The Toll pathway is important for an antiviral response in Drosophila. PNAS 102: 7257-7262 (2005). [pdf]

Pal, S., L. Wu. Guts and Glory: Balancing Microbes and the Immune Response. Developmental Cell 8: 1-2 (2005). [pdf]

Wu, L., K.-M. Choe, Y. Lu, K. Anderson. Drosophila Immunity: Genes on the Third Chromosome Required for the Response to Bacterial Infection. Genetics 159: 189-199 (2001). [pdf]

Lu, Y., L. Wu, K. Anderson. The antibacterial arm of the Drosophila innate immune response requires an I{kappa}B kinase. Genes and Development, 15: 104-110 (2001). [pdf]

Wu, L., K. Anderson. Regulated nuclear import of Rel proteins in the Drosophila Immune Response. Nature 392: 93-7 (1998). [pdf]